Wilson's Disease: An Overview of the Disease and an Approach for the Primary Care Physician

Wilson's disease (WD) is a copper metabolism disorder that inherited in an autosomal recessive manner, which produces toxic accumulation of mainly the liver and brain, general it has two forms presentation, hepatic more prevalent at early ages neurological one occurs later ages. Although WD not common disease, should be suspected all chronic undetermined etiology with negative viral markers autoimmunity, either or without manifestations, as soon possible thus start treatment chelators, leads to substantial improvement prognosis these patients.